Endocrine Abstracts

Drug-induced vasculitis or lupus-like syndromes can complicate the clinical course of PTU-treated patients. The clinical manifestations of four patients treated with PTU for Graves’ disease are presented.A 37-year-old woman was treated with PTU for six years. She had severe thyrotoxicosis, high fever and polyarthralgia. Elevated doses of PTU resulted in normalization of thyroid function, but the fever and arthralgia persisted even after steroid admi...